Endocrine Abstracts

Aim: The relationship between hyperprolactinoma and insulin resistance has been shown in many studies. It is also known that hyperprolactinoma causes changes in carbohydrate and lipid metabolism. The aim of our study is to evaluate insulin resistance in patients with prolactinoma and see the effect of treatment on insulin resistance and karotis intima media thickness (CIMT).Material and methods: Twenty-two female patients diagnosed biochemically and radi...

Objective: Hyperprolactinemia is reported to be associated with impaired glucose metabolism, and low-grade inflammation. There is some data regarding increased oxidative stress- particularly protein oxidation in the conditions like metabolic syndrome or diabetes, but not in hyperprolactinemic subjects in the literature. We aimed to investigate advanced oxidation protein product (AOPP) levels-an established marker of protein oxidation and antioxidant thiol levels in hyperprolac...

Aim: Hypogonadism is a result of testicular failure and/or insufficient pituitary stimulation. Various hypothalamo-pituitary abnormalities or lesions can contribute to hypogonadism. Benign or malign tumoural lesions of cellar or paracellar region, may lead to hypogonadism. Therefore, pituitary magnetic resonance imaging (MRI), is needed in hypogonadic patients. In our study, we aimed to investigate our hypogonadic patients’ hypothalamo-pituitary MRI findings.<p class=...

Background: We investigated the frequency for diagnosis of Hashimoto’s thyroiditis (HT) in obstructive sleep apnea (OSA) patients, based on rising interest in potential links of OSA’s pathogenesis with impaired auto-immune mechanisms.Design and methods: Polysomnography was performed to 245 euthyroid eligible subjects consecutively. Study population divided according to apnea-hypopnea index (AHI) as control (n=59, AHI<5), mild OSA (<i...

Aim: Antineutrophil cytoplasmic antibody (ANCA) positivity is usually determined in medium and large vessel vasculitis. This antibody has two different forms. Cytoplasmic ANCA (PR3-ANCA) occurs against proteinase-3, while perinuclear ANCA (MPO-ANCA) occurs against myeloperoxidase and bactericidal- permeability increasing proteins. The presence of ANCA is mostly seen in systemic vasculitis and also in drug induced vasculitis. There is no sufficient data about prevalence of posi...

Aim: In this study, we aimed to evaluate thyroid functions, thyroid antibody positivity, thyroid ultrasonography (US) findings and prevalence of thyroid cancer in patients with colon cancer and benign colon polyps. Also, we aimed to compare prevalence of thyroid diseases in two groups.Materials and methods: Fifty-seven patients with colon cancer and 50 patients with colon polyps were included in the study. All patients were evaluated with thyroid US and ...

Aim: Radioactive treatment after surgery forms the basis of treatment of differentiated thyroid cancers (DTC) and also used as permanent theraphy of hyperthyroidism. Iodide is being transported into the thyrocytes by the NIS system that located on the thyrocytes’ cell membran. NIS system also has been shown at the gastric mucosa. In this study we proposed to analyse the effect of low and high dose radio-iodine treatment on Helicobacter pylori eradication.<p cla...

Aim: In our study, we aimed to evaluate the cytologic findings of the thyroid nodules, in which macrocalcification is determined with ultrasonography.Method: We evaluated retrospectively 907 nodules of 269 patients, who have nodular or multinodular goiter and have macrocalcification at least in one nodule. The same patients’ nodules that don’t have macrocalcification are taken into the control group. Patient’s thyroid function tests, ultra...

Aim: Neopterin is a mareker of inflammation secreted from monocytes and macrophages. It is found to be increased in malignant diseases. The aim this study was to evaluate the urine neopterin levels in thyroid cancer.Materials and methods: Sixty nine patients with thyroid cancer, 76 patients with benign thyroid pathology and 33 healthy subjects were evaluated. First morning urine samples were collected from the patients and the normal subjects for neopter...

Objective: In this study, we aimed to evaluate ultrasonographical and elastosonographical characteristics, cytological results and histopathological features of nodules in patients with Hurthle cells in cytological examination and operated for various reasons.Method:57 patients and 57 nodules detected to have Hurthle cells in thyroid fine needle aspiration biopsy (FNAB) were included in the study.Results: Among 57 nodules with Hurt...